Longevity for Founders & Executives

More life
in every year

Advanced testing, early action, and science-backed strategies to stay in your prime, longer.

Trusted by 500+ founders & executives from

The Problem

Something’s off, and your physical
keeps missing it.

Energy
Tired all the time.

The crash hits like clockwork, and coffee stopped touching it.

Sleep
Poor recovery.

Workouts that used to take a day to recover from now take a week.

Metabolism
Can’t lose weight.

The same routine that always worked just… doesn’t anymore.

Vitality
Low drive.

The natural edge that made you successful now takes effort to find.

Focus
Brain fog.

Words go missing mid-sentence and focus slips by mid-morning.

Bloodwork
“Normal” results.

You’re told your labs are fine, but you know something isn’t right.

Your symptoms are real, and your answers are hidden in data that was never measured.

Deeper tests, higher standards, and expert-led care.

A standard physical scores a couple dozen markers against ranges built for the average patient. The early drift, years before any symptom, slips right through.

201,000+

Biomarkers we map across hormones, metabolism, heart, brain, gut, and inflammation. Your annual physical checks fewer than 20.

Optimal

Every marker graded against elite standards. “Normal” only flags disease once it’s already here.

One team

Labs, nutrition, training, supplements, and sleep, run by one team with the full picture.

Find what’s been missed → It’s in your data. It always was.
The Mission

Welcome to your second prime.

Leaders like you spent your first prime building a successful life. Most people will never understand the sacrifices you’ve had to make to get here.

We believe your health doesn’t have to be one of them.

Second Prime exists to bring world-class health and longevity to leaders who have no interest in being average. We’re here to make sure your best years are still ahead of you.

Our Method

How it works

Deep testing, real interpretation, and an actual game plan. All of it done for you, from wherever you are.

Client Voices

In their words

Founders and executives who stopped settling for “normal.” Anonymized for privacy.

“I’ve sent three people to Andrew already. I don’t do that unless something actually worked.”

MD
Mark D.
Investment Banking, 47

“I kept telling myself the brain fog was just stress. It wasn’t stress. Three months in and I’m sharper.”

DK
David K.
Partner, Law, 48

“My wife actually said something to me about two months in. More present, more patient, actually there.”

BW
Brian W.
Operator, Govt Contracting, 52

“I’ve sent three people to Andrew already. I don’t do that unless something actually worked.”

MD
Mark D.
Investment Banking, 47

“I kept telling myself the brain fog was just stress. It wasn’t stress. Three months in and I’m sharper.”

DK
David K.
Partner, Law, 48

“My wife actually said something to me about two months in. More present, more patient, actually there.”

BW
Brian W.
Operator, Govt Contracting, 52

“My cardiologist had watched my ApoB and Lp(a) for three years. Nothing moved it. Six months here did.”

JL
J. L.
CEO, Logistics, 52

“I came in skeptical. I’d done bloodwork a dozen times. Andrew found things in week one nobody had flagged.”

RS
R. S.
Founder, Tech, 44

“I had a cardiologist, a trainer, a nutritionist. None of them talked. I was the one connecting the dots.”

MK
M. K.
Executive, Asset Mgmt, 46

“My cardiologist had watched my ApoB and Lp(a) for three years. Nothing moved it. Six months here did.”

JL
J. L.
CEO, Logistics, 52

“I came in skeptical. I’d done bloodwork a dozen times. Andrew found things in week one nobody had flagged.”

RS
R. S.
Founder, Tech, 44

“I had a cardiologist, a trainer, a nutritionist. None of them talked. I was the one connecting the dots.”

MK
M. K.
Executive, Asset Mgmt, 46

“I used to need two coffees before 9am to feel human. Now I get through back-to-back days without the wall.”

DR
D. R.
Construction CEO, 52

“There were months I was making decisions I knew weren’t sharp. The fog is gone. I think clearly again.”

TK
T. K.
Asset Management, 46

“I hadn’t slept properly in years. Within 60 days my HRV doubled and I wake up actually recovered.”

JM
J. M.
Real Estate Founder, 48

“I used to need two coffees before 9am to feel human. Now I get through back-to-back days without the wall.”

DR
D. R.
Construction CEO, 52

“There were months I was making decisions I knew weren’t sharp. The fog is gone. I think clearly again.”

TK
T. K.
Asset Management, 46

“I hadn’t slept properly in years. Within 60 days my HRV doubled and I wake up actually recovered.”

JM
J. M.
Real Estate Founder, 48
What We Actually Do

We do three things

Every test, protocol, and adjustment in the program serves one of these.

The Executive Assessment

The deepest look you've ever had at your own biology

Everything is coordinated for you: draws near your home or office, kits shipped to your door, results interpreted by people who know what optimal looks like.

Advanced Cardiovascular PanelApoB, Lp(a), hs-CRP, 60+ more.
MicronutrientsVitamins, minerals, deficiencies.
InflammationThe slow burn behind fog and fatigue.
Serum HormonesTestosterone, thyroid, cortisol.
Metabolic FunctionInsulin and glucose, in depth.
Brain HealthHomocysteine, omega-3, cognition.
Organ FunctionLiver, kidney, filtration health.
Biological AgeYour true age, tracked yearly.
Gut Microbiome AnalysisWhat your gut does to you.
Salivary & Urinary HormonesCortisol rhythm and metabolism.
Food ReactivityThe foods working against you.
Toxic ExposureHeavy metals and toxins.
DEXA ScanLean mass, fat, bone density.
VO₂ MaxThe strongest longevity predictor.
Mobility AssessmentWhere movement costs you power.
Strength TestingStrength benchmarked to your age.
Nutritional AnalysisWhat you eat vs. what you need.
Lifestyle AnalysisSleep, stress, and training load.
Resilience ProfileSleep, stress, recovery in one view.
Genetic TestingApoE to methylation, decoded.
Full-Body MRICatches what bloodwork can't.Second Prime Black Exclusive
Early Cancer ScreeningMulti-cancer early detection.Second Prime Black Exclusive
From Data to Plan

A plan you can actually run

The hard part is knowing which few of the 1,000 data points matter right now, building the plan, and running it with you. That's the whole job.

From everything to what matters
1,000+
markers measured
134
outside optimal
23
address now
7
urgent

Illustrative first assessment. Your numbers will be your own.

Priority 1 Cardiovascular risk: elevated ApoB Targeted lipid protocol, blood pressure work, 12-week re-test.
Priority 2 Early insulin resistance 16-week nutrition and strength block, glucose re-check.
Priority 3 Recovery debt: poor sleep quality Sleep protocol with wearable tracking, reviewed monthly.

Example of a client's first-quarter plan.

Andrew Martin, founder of Second Prime
Meet the Founder

I trained as a scientist. I’ve spent a decade dialing in real people’s biology.

I’m Andrew Martin. My background is in biology and biochemistry, and I started in a research lab, studying human physiology at the level of the cell and the pathway, the depth where most people’s understanding of their own health runs out. I didn’t want to study it under glass. I wanted to use it on real people.

That was more than a decade ago. Since then I’ve worked one-to-one with over 1,000 clients, more than 500 of them founders and executives, reading their biology and building the protocol that actually moves it. Few practitioners have looked at this much human data, this closely, for this long.

I also lived the problem. In my prime, an autoimmune condition leveled me, and close to $20,000 of specialists couldn’t say why. I ran my own comprehensive assessment, found the Epstein-Barr infection driving it, and resolved it with a protocol built from the data. That became the method behind Second Prime.

10+ yrsone-to-one in practice
1,000+clients served
500+founders & executives
Read my full story →
Who It's For

Built for people who perform for a living

Founder

Founders

Brain fog in the afternoons. Stubborn fat that diet alone won't touch. Energy that crashes right when the company needs you most. You've outworked everything except your own biology.

Executive

Executives

Sharpness that isn't what it was. Sleep that doesn't restore. A caffeine dependency doing the work your hormones used to do. Decisions feel slower, and you've noticed.

High performer

High performers

Former pro athletes, actors, musicians, the relentlessly driven. Performance has always been the job. Now you want recovery, energy, and longevity engineered the same way: on data, not guesswork.

Case Studies

Measured results.

Clients who stopped settling for “normal,” shared with their permission.

Individual results vary and are not typical or guaranteed. Shared with permission.

Seen enough numbers?

A 30-minute conversation tells you if this is a fit. Zero pressure, zero homework.

Book a Consult →
Questions

Frequently asked questions

Still unsure? Book a 30-minute consult. Zero pressure.

Your doctor's job is to find disease, and they're good at it. Our job is everything before that: the decade where your labs read “normal” but your energy, body, and sharpness say otherwise. We test 1,000+ markers instead of fewer than 20, grade them against optimal instead of normal, and then actually run the plan with you.

Founders and executives in their 40s and beyond, running at high output and intent on keeping it. Former athletes who want their edge back. People with a family history they'd rather get ahead of. What they share is a readiness to act on the findings and run the plan with us.

If you're after a quick fix, a generic 12-week challenge, or someone to supply your motivation, we're not your team. We work on root causes, and the protocol only pays off when you run it. We say this up front because the people who get the most from Second Prime are the ones who came to do the work.

“Fine” is usually the question, not the answer. Most clients come in feeling fine and discover hormonal, metabolic, or cardiovascular drift their physical never measured. Catching that decline early is the entire advantage.

Three things. A deep assessment that maps 1,000+ data points across your blood, hormones, metabolism, gut, body composition, and fitness. A personalized Performance Blueprint built from it: nutrition, training, sleep, supplements, and advanced therapies where they're warranted. And a team that runs the plan with you, with everything coordinated and shipped to your door.

Most clients notice real shifts in energy, sleep, and focus within the first 8 to 12 weeks, as the early protocol changes take hold. Deeper markers like ApoB, inflammation, and body composition move over quarters, which is why we re-test every 90 days and adjust.

When your data calls for it and a physician signs off, yes. Hormone therapy and peptides are part of the toolkit, used with medical oversight and ongoing monitoring through our medical partner. Nothing is prescribed by default. It's prescribed because your numbers warrant it.

Second Prime is a premium, done-for-you program and it's priced accordingly. There are two levels depending on how hands-on you want us to be. We'll walk you through which one fits and the exact investment on your consult, with no pressure to decide on the call.

No travel required. Blood draws are coordinated near your home or office, kits ship to your door, scans like DEXA are scheduled at facilities in your area, and every review happens over video with your team.

Less than you'd think. The assessment phase takes about 20 days of mostly waiting, not doing. After that, your team handles the logistics and you handle the living. The plan is built to fit a real schedule, not a monk's.

Anything clinical goes straight to physician review through our medical partner, and we help you get to the right specialist quickly. Then we keep working the plan around it.

Andrew Martin, a biologist who built the method on himself first, leads a team of performance coaches, with physician oversight through our medical partner. Small by design and capped at 50 clients for 2026.